ISS: Expedition 4

Launch from Cape Canaveral (KSC); landing on Edwards AFB.

Following a two day solo flight the Endeavour docked on December 07, 2001 to the ISS. The crew replaced the expedition 3 crew. While at the station, STS-108 conducted one spacewalk and attached the Raffaello Multi-Purpose Logistics Module to the station so that about 2.7 metric tons (3 tons) of equipment and supplies could be unloaded. The crew later returned Raffaello to Endeavour's payload bay for the trip home.

The first EVA by Yuri Onufriyenko and Carl Walz occured on January 14, 2002 (6h 3m) to move a Strela cargo crane and install an amateur radio antenna.

The second EVA was performed by Yuri Onufriyenko and Daniel Bursch on January 25, 2002 (5h 59m) to install six thruster deflectors at the rear of the Zvezda Service Module, retrieving and replacing a device to measure material from the thrusters and installing a ham radio antenna and its cabling.

The third and final EVA by Carl Walz and Daniel Bursch occured on February 20, 2002 (5h 47m) to perform housekeeping chores and gather tools to prepare for the next station assembly mission, which will deliver the central section of the outpost's backbone.

On April 20, 2002, Yuri Onufriyenko relocated the Soyuz TM-33 rescue capsule from the Zarya module to the Pirs docking compartment (21 m).

Common work with the visiting crews of STS-110 (April 10, - April 17, 2002) and Soyuz TM-34 (April 25, - May 05, 2002) was done. The main purpose of STS-110 was to attach the S0 Truss segment to the International Space Station (ISS) to the Destiny Laboratory Module. It forms the backbone of the station to which the S1 and P1 truss segments were attached (on the following missions STS-112 and STS-113, respectively). STS-110 also delivered the Mobile Transporter (MT), which is an 885 kilograms (1,950 lb) (1,950 lb) assembly that glides down rails on the station integrated trusses.

During the stay on board of the ISS the crew of expedition 4 carried out the following scientific experiments:
ADF-Otolith (Avian Development Facility - Development and Function of the Avian Otolith System in Normal Altered Gravity Environments),
ADF-Skeletal (Avian Development Facility - Skeletal Development in Embryonic Quail),
ADVASC (Advanced Astroculture),
Alteino (Space Radiation Effects on the Central Nervous System),
ARIS-ICE (Active Rack Isolation System - ISS Characterization Experiment),
ARISS (Amateur Radio on the International Space Station),
Biotest (Biochemical Status of Humans in Long Duration Space Flight),
BPS (Biomass Production System),
Brados (Acquisition of Data About the Radiological, Electromagnetic and Different Physical Environments on Board ISS, and Their Effects on the Safety of the Crew, Space Equipment and Materials),
Cardio-ODNT (Dynamics of the Main Factors of Cardiac Function, of Central and Regional Circulation in Rest and During the Influence of Lower Body Negative Pressure),
CBOSS-01-02-Renal (Cellular Biotechnology Operations Support Systems: Human Renal Cortical Cell Differentiation and Hormone Production),
CBOSS-02-Erythropoietin (Cellular Biotechnology Operations Support Systems: Production of Recombinant Human Erythropoietin by Mammalian Cells),
CBOSS-02-HLT (Cellular Biotechnology Operations Support Systems: The Effect of Microgravity on the Immune Function of Human Lymphoid Tissue),
CBTM (Commercial Biomedical Testing Module: Effects of Osteoprotegerin on Bone Maintenance in Microgravity),
CCE (Cardiovascular Responses During Rest and Exercise, and Evaluation of Energy Inputs During Exercise),
CEO (Crew Earth Observations),
CGBA-APS (Commercial Generic Bioprocessing Apparatus - Antibiotic Production in Space),
Chromosome-1 (Chromosomal Aberrations in Blood Lymphocytes of Astronauts-1),
Clinical Nutrition Assessment (Clinical Nutrition Assessment of ISS Astronauts, SMO-016E),
CPCG-H (Commercial Protein Crystal Growth - High Density),
Diatomeya (Stability of Geographical Position and Configuration of Borders of Bioproductive Water Zones of the World Oceans, Observations by Orbition Station Crews),
Diurez (Fluid and Electrolyte Metabolism and Hormonal Regulaltion of Fluid Volume),
EarthKAM (Earth Knowledge Acquired by Middle School Students),
Education-SA (Education - South Africa: Demonstration of Mass and Weight of Objects, and Action of Reactive Forces in Microgravity),
Environmental Monitoring (Environmental Monitoring of the International Space Station),
EPO (Education Payload Operations),
ESA-GCF (European Space Agency - Granada Crystallisation Facility),
ESCD (Study of Embryonic and Stem Cell Development in Microgravity),
EVARM (A Study of Radiation Doses Experienced by Astronauts in EVA),
EXPPCS (EXPRESS Physics of Colloids in Space),
Farma (Characteristics of Pharmacological Responses (absorption, distribution and elimination of acetominophene) in Long Duration Space Flight),
H-Reflex (Effects of Altered Gravity on Spinal Cord Excitability),
Identifikatsia (Identification of the Sources of Dynamic Loads on ISS ),
Inflight Education Downlinks (International Space Station Inflight Education Downlinks),
Interactions (Crewmember and Crew-Ground Interaction During International Space Station Missions),
Iskazheniye (Determination and Analysis of Magnetic Interference on ISS),
ISS Acoustics (International Space Station Acoustic Measurement Program),
Izgib (Effect of Performance of Flight and Science Activities on the Function of On-Orbit Systems on ISS (Mathematical Model)),
Kolibry (Developmental Testing of the Kolibry Microsatellite Deployment Profile),
Konstructor (Filming of Space Robot "Jitter" Assembled out of Legos),
Kromka (Verification of the Effectiveness of Devices for the Protection of the Exterior Surface of ISS from Contaminants Deposited by Pulsed Cycling of Liquid-Jet),
Latent Virus (Incidence of Latent Virus Shedding During Space Flight),
Meteoroid (Recording Meteoroidal and Technogenic Particles on the External Surface of the Service Module of the Russian Segment of ISS),
MISSE-1 and 2 (Materials International Space Station Experiment - 1 and 2),
Molniya-SM (Investigation of Lightning Discharges in the Earth's Atmosphere and Lower Ionosphere),
Paradont (Condition of Peridontal Tissues in Space Flight),
PCG-EGN (Protein Crystal Growth-Enhanced Gaseous Nitrogen Dewar),
PCG-STES-IDQC (Protein Crystal Growth-Single Locker Thermal Enclosure System-Improved Diffraction Quality of Crystals),
PCG-STES-MM (Protein Crystal Growth-Single Locker Thermal Enclosure System-Synchrotron Based Mosaicity Measurements of Crystal Quality and Theoretical Modeling),
PCG-STES-SA (Protein Crystal Growth-Single Locker Thermal Enclosure System-Science and Applications of Facility Hardware for Protein Crystal Growth),
PCG-STES-VEKS (Protein Crystal Growth-Single Locker Thermal Enclosure System-Vapor Equilibrium Kinetics Studies),
PESTO (Photosynthesis Experiment and System Testing and Operation),
Plankton-Linza-SA (Characterizing the Effects of Atmospheric, Hydrophysical and Geological Factors on Biological Productivity of Oceanic Waters Surrounding The Republic of South Africa),
Platan (Search for Low Energy Heavy Particles of Solar and Galactic Origin),
Privyazka (Development of High Precision Orientation of Scientific Devices in Space with Reports of Deformation of the ISS Hull),
Profilaktika (Mechanisms of Action and Influence, and Effectiveness of Various Methods of Phrophylaxis Directed Toward Prevention of Disturbances of the Human Locomotion System in Weightlessness),
Prognoz (Development of a Method of Operational Prediction of Work Load on Crew Piloting Objectives),
PuFF (The Effects of EVA and Long-Term Exposure to Microgravity on Pulmonary Function),
Relaksatia (Processes of Relaxation in the Ultraviolet Band Spectrum by High Velocity Interaction of Exhaust Products on ISS),
Renal_Stone (Renal Stone Risk During Spaceflight: Assessment and Countermeasure Validation),
SKR (Skorpion: Development and Acquisition of Multifunctional Control-Measurement Device for Controlling the Environment of Scientific Experiments Inside a Pressurized Station),
SPC (Soluble Protein Crystallization: Obtaining Crystals of Soluble Proteins FcgIII and FcgeII with a Perfect Crystal Structure),
Subregional_Bone (Subregional Assessment of Bone Loss in the Axial Skeleton in Long-term Space Flight),
Tenzor (Definition of Dynamic Characteristics of ISS),
Uragan (Hurricane: Experimental Development of Groundbased System of Monitoring and Predicting the Progression of a Naturally Occurring Technogenic Catastrophe),
Vektor-T (Study of a High Precision System for Prediction Motion of ISS),
Vzglyad (Photographing the Interior of ISS),
Xenon1 (Effect of Microgravity on the Peripheral Subcutaneous Veno-Arteriolar Reflex in Humans),
ZCG (Zeolite Crystal Growth).