Launch from Cape Canaveral (KSC); landing on Cape Canaveral (KSC).

The primary payloads were the USMP-02 microgravity experiments package and the OAST-2 engineering and technology payload, both in the orbiter's cargo bay. The two week mission also featured a number of biomedical experiments focusing on the effects of long duration spaceflight.

On experiment on USMP-02 was the Isothermal Dendritic Growth Experiment (IDGE). That experiment continued to assemble data to test theories concerning the effect of gravity-driven fluid flows on dendritic solidification of molten materials.

OAST-2 contained six experiments on the field of technology for the space station, satellites, sensors and more.

STS-62 carried several secondary payloads as crystal growth experiments, medical and fluid experiments.