Launch from the Baikonur Cosmodrome; landing with Soyuz T-11 capsule 46 km east of Arkalyk.

Following a one day solo flight Soyuz T-10 docked with Salyut 7 on February 02, 1984. The cosmonauts became the third resident crew of the station. The crew entered the darkened Salyut 7 station carrying flashlights. The cosmonauts commented on the burnt-metal odor of the drogue docking unit, but the station became fully activated.

Several medical experiments under the lead of Oleg Atkov were performed. The resident crew became visits of the spacecrafts Soyuz T-11 on April 03, 1984 and Soyuz T-12 on July 17, 1984. Also five supply missions with cargo spaceships Progress 19 - 23 arrived at the station.

The first EVA was performed by Leonid Kizim and Vladimir Soloviyov on April 23, 1984 (4h 15m). The cosmonauts attached the ladder and prepared the repair site. The propulsion system with main oxidiser line was ruptured in September 1983. Progress 20 delivered a special ladder for reaching the area of the damaged line.

The second spacewalk occurred on April 26, 1984 (4h 56m). Leonid Kizim and Vladimir Soloviyov cut through thermal insulation and the stations hull to reach the damaged plumbing. They installed a valve in the reserve propellant line before going back inside Salyut 7.

The third EVA on April 29, 1984 (2h 45m) was conducted by the same cosmonauts. They installed a new propellant line to bypass the damaged section.

Leonid Kizim and Vladimir Soloviyov performed the fourth spacewalk on May 03, 1984 (2h 45m). The cosmonauts installed a second bypass line and covered the opening in Salyut 7s side with thermal insulation. However, they were unable to complete repairs because they lacked tools to close the bypassed propellant line.

Progress 21 docked with Salyut 7 on May 10, 1984 and delivered two 9 m2 solar array extensions. They were added in the fifth EVA by Leonid Kizim and Vladimir Soloviyov on May 18, 1984 (3h 05m).

The sixth and final EVA occurred on August 08, 1984 (5h 00m). A pneumatic hand press, delivered by Soyuz T-12, was used to crush both ends of the bypassed fuel line, sealing it. Anatoli Soloviyov and Leonid Kizim also collected a piece of a solar array for analysis.

A new spaceflight record was set.