Launch from the Baikonur Cosmodrome; landing 65 km northeast of Arkalyk.

Following a one day solo flight Soyuz T-6 docked manually with the Salyut 7 space station on June 25, 1982 because of problems with the automatic docking systems. Common work with the first resident crew was done.

Several joint Soviet-French scientific research and experiments, including a series of French echography cardiovascular monitoring system experiments, were performed. Jean-Loup Chrétien was the first French and West European astronaut. While aboard the station, the resident crew afforded him the opportunity to eject Salyut 7's weekly bag of waste into space through the station's small trash airlock. Valentin Lebedev, writing in his diary, quoted Jean-Loup Chrétien as saying Salyut 7 "is simple, doesn't look impressive, but is reliable."