Launch from Cape Canaveral (KSC). First night launch of the Apollo program. The launch had been delayed 2 hours 40 minutes by a countdown sequencer failure. Landing 560 km west of Samoa Islands in the Pacific Ocean.

Final moonlanding with the LM Challenger. Landing site: Taurus Littrow highlands and valley area. The crew performed a heat flow and convection demonstration and an Apollo light flash experiment during the translunar coast. Lunar surface staying time: 75 hours. Three EVAs were performed by Cernan and Schmitt. First EVA on 11.12.1972 (7h 12m), in which the ALSEP was deployed, two geological units were sampled, two explosive packages were deployed and seven traverse gravimeter measurements were taken, among other work.

Second EVA on 12.12.1972 (7h 37m). During this EVA the crew discovered orange soil near the Shorty Crater. Five surface samples and double core samples were taken in this area. Three explosive packages were deployed and seven traverse gravimeter measurements were taken. Observations were be photographed.

The final EVA on the lunar surface for long time on 13.12.1972 (7h 19m). They collected specific samples (basalts, rocks, soil). This time nine traverse gravimeter measurements were taken. At least a plaque on the landing gear of the lunar module, commemorating all of the Apollo lunar landings, was unveiled. All in all 110.4 kg of lunar samples had been collected. Gene Cernan became the last man on the moon

While both astronauts were exploring the lunar surface, Evans was conducting numerous scientific activities in the CSM (America) in lunar orbit, using for example the three new scientific module experiments (infrared radiometer, ultraviolet spectrometer and a lunar sounder),

Evans also performed a trans Earth EVA on 17.12.1972 (1h 6m) to recover several film cassettes, and the crew conducted again several scientific experiments.

The recovery ship was the USS Ticonderoga.